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Human protein C has at least five types of post-translational modifications: (1) gamma- carboxylation on the first nine glutamic acid. The protein C anticoagulant pathway serves as a major system for controlling thrombosis, limiting inflammatory. The Protein C Pathway* Charles T. Esmon, PhD The protein C anticoagulant pathway serves as a major system for controlling. The protein C anticoagulant pathway serves as a major system for controlling thrombosis, limiting inflammatory responses, and. Indeed, the protein C system is now emerging as a novel participant in the pathogenesis of acute and chronic.

Recently, novel and unexpected roles of hemostasis in the humoral and cellular components of innate immunity have been described..